Metvix Cream
Galderma
Description
After topical application of Metvix (methyl aminolevulinate), porphyrins accumulate intracellularly in the treated skin lesions. The intracellular porphyrins (including PplX) are photoactive, fluorescing compounds and, on light activation in the presence of oxygen, singlet oxygen is formed, which causes damage to cellular compartments, in particular the mitochondria. Light activation of accumulated porphyrins leads to a photochemical reaction and thereby phototoxicity to the light-exposed target cells
Indications
For the treatment of thin or non-hyperkeratotic and non-pigmented actinic keratoses on the face and scalp when other therapies are considered less appropriate. Only for treatment of superficial and/or nodular basal cell carcinoma; unsuitable for other available therapies due to possible treatment-related morbidity and poor cosmetic outcome, such as lesions on the mid-face or ears, lesions on severely sun damaged skin, large lesions, or recurrent lesions. Treatment of squamous cell carcinoma in situ (Bowen’s disease), when surgical excision is considered less appropriate
Price
2g, £157.40
More on: Actinic keratoses treatments