Dermatology Handbook

The professional's guide to product selection

Topical treatments

Acea

Acea

Acea 0.75% w/w Gel is a water based gel containing 0.75% w/w of the active ingredient metronidazole. Acea Gel is used for the treatment of rosacea, a skin condition usually affecting the facial cheeks and forehead in which the skin appears redder than normal. Acea Gel belongs the group of medicines Antiprotozoal and Antibacterial Agents, which are used to control infection and inflammation in skin problems.

Acnecide

Acnecide

Acnecide is a 5% preparation of benzoyl peroxide, which is an established and effective keratolytic agent with antibacterial properties. It has been shown to be effective in reducing the local population of Propionibacterium acnes, leading to a reduction in the production of irritant fatty acids in the sebaceous glands

Actikerall

Actikerall

Actikerall is a combination of fluorouracil and salicylic acid. The active substance fluorouracil (FU) is a cytostatic agent that has an antimetabolite effect. Topical salicylic acid has a keratolytic effect and reduces the hyperkeratosis associated with actinic keratosis

Akincare

Akincare

Akincare contains triethyl citrate 4% and ethyl linoleate 2%

Aknemycin Plus

Aknemycin Plus

Aknemycin Plus is a combination of a retinoid and antibacterial in an alcohol base that dissolves sebum. The retinoid tretinoin acts topically as a keratolytic agent by markedly increasing cell turnover in the cornified epithelium, including the epithelium of the follicular ducts and comedones. In the first instance, skin irritation, erythema and increased vascularisation occur, followed by thickening and desquamation of the epithelium. The renewal time of the cornified epithelium is therefore shortened. Erythromycin is a macrolide antibiotic with bacteriostatic action on all pathogens involved in the development of acne. When applied topically, it also effects a reduction in the concentration of skin surface lipids and shows a direct anti-inflammatory effect

Aldara

Aldara

Aldara contains imiquimod, an immune response modifier. It is effective against viral infections and acts as an anti-tumour agent, principally by induction of alpha interferon and other cytokines

Alphosyl 2-in-1

Alphosyl 2-in-1

Alphosyl 2-in-1 contains coal tar, which has keratolytic and keratoplastic properties and aids treatment by slowing the excessive epidermal cell turnover

Ameluz

Ameluz

Following topical application of Ameluz, a 5-aminolaevulinic acid, the substance is metabolised to protoporphyrin IX, a photoactive compound which accumulates intracellularly in the treated actinic keratosis lesions. Protoporphyrin IX is activated by illumination with red light of a suitable wavelength and energy. In the presence of oxygen, reactive oxygen species are formed. The latter causes damage of cellular components and eventually destroys the target cells.

Anabact

Anabact

Anabact contains 0.75% metronidazole, which is an established antibacterial agent. It is effective against a variety of organisms including anaerobic bacteria, which are responsible for the distressing symptoms of malodorous thickness wounds.

Bactroban

Bactroban

Bactroban contains mupirocin, an antibiotic. It has bacteriostatic properties at minimum inhibitory concentrations and bactericidal properties at the higher concentrations reached when applied locally

Betacap Scalp Application

Betacap Scalp Application

Betacap Scalp Application complies with the specification given in the monograph for betamethasone valerate scalp application BP. Betacap Scalp Application includes a coconut-oil related emollient ingredient to reduce the drying effect that a standard alcoholic vehicle may otherwise have on the scalp. The vehicle also contains isopropyl alcohol, which has antiseptic activity

Betnovate

Betnovate

Betamethasone valerate is potent corticosteroid with topical anti-inflammatory activity and pruritic manifestations of steroid responsive dermatoses

Betnovate Scalp Application

Betnovate Scalp Application

Betamethasone valerate is potent corticosteroid with topical anti-inflammatory activity and pruritic manifestations of steroid responsive

Betnovate-RD

Betnovate-RD

Betamethasone is a corticosteroid with topical anti-inflammatory activity. Betamethasone valerate ready diluted (Betnovate RD) preparations are indicated for maintenance treatment once an acute episode has been treated effectively with a continuous course of betamethasone valerate (Betnovate).

Bettamousse

Bettamousse

Bettamousse contains betamethasone, a glucocorticosteroid that has topical anti-inflammatory activity. Bettamousse is used for the treatment of steroid-responsive dermatoses of the scalp, such as psoriasis. Topical application by massaging into the affected areas. Contains betamethasone valerate, a glucocorticosteroid which has topical anti-inflammatory activity.

Calcipotriol 50 micrograms/ml Ointment

Calcipotriol 50 micrograms/ml Ointment

Calcipotriol is a vitamin D derivative. In vitro data show that calcipotriol induces differentiation and suppresses proliferation of keratinocytes. The effect of calcipotriol in psoriasis is ascribed mainly to this. 

Calcipotriol 50 micrograms/ml Scalp Solution

Calcipotriol 50 micrograms/ml Scalp Solution

Calcipotriol is a vitamin D derivative. In vitro data show that calcipotriol induces differentiation and suppresses proliferation of keratinocytes. The effect of calcipotriol in psoriasis is ascribed mainly to this. 

Canesten

Canesten

Canesten contains clotrimazole, which is an imidazole derivative with a broad spectrum of antimycotic activity that includes dermatophytes, yeasts and moulds. The mode of action of clotrimazole is fungistatic or fungicidal, depending on the concentration of clotrimazole at the site of infection. Primarily resistant variants of sensitive fungal species are very rare; the development of secondary resistance by sensitive fungi has been observed only in very isolated cases under therapeutic conditions.

Canesten HC

Canesten HC

Canesten HC is a broad-spectrum antimycotic and is a combination of clotrimazole (an imidazole derivative) and hydrocortisone (a glucocorticoid). Clotrimazole is a broad-spectrum antifungal. It also exhibits activity against Trichomonas, Staphylococcus, Streptococcus and Bacteroides

Canesten Hydrocortisone

Canesten Hydrocortisone

Canesten Hydrocortisone is a combination of clotrimazole and hydrocortisone acetate. Clotrimazole belongs to a group of medicines called imidazoles, which destroy the fungi and some bacteria that cause skin infections. Hydrocortisone acetate is a mild steroid which reduces swelling, redness and itching associated with inflammation of the skin

Capasal Therapeutic Shampoo

Capasal Therapeutic Shampoo

Capasal Therapeutic Shampoo has been designed as an aid in the treatment of dry, scaly scalp conditions by incorporating three ingredients that are established as safe and effective for use in this indication: 0.5% salicylic acid (mild keratolytic), 1.0% coconut oil (emollient, softening agent and lubricant) and 1.0% distilled coal tar (antipruritic, keratoplastic)

Care Hydrogen Peroxide Solution 3%

Care Hydrogen Peroxide Solution 3%

A mild disinfectant to use as a mouthwash or gargle for people over 12 years old, or as an effective way to disinfect minor cuts, wounds and skin ulcers on adults, children and the elderly. Pregnant or breastfeeding mothers should only use if advised by the doctor.

Care Hydrogen Peroxide Solution 6%

Care Hydrogen Peroxide Solution 6%

A mild disinfectant to use as a mouthwash or gargle for people over 12 years old, or as an effective way to disinfect minor cuts, wounds and skin ulcers on adults, children and the elderly. Pregnant or breastfeeding mothers should only use if advised by the doctor.

Care Hydrogen Peroxide Solution 9%

Care Hydrogen Peroxide Solution 9%

A mild disinfectant to use as a mouthwash or gargle for people over 12 years old, or as an effective way to disinfect minor cuts, wounds and skin ulcers on adults, children and the elderly. Pregnant or breastfeeding mothers should only use if advised by the doctor.

Care Magnesium Sulfate Paste BP

Care Magnesium Sulfate Paste BP

A drawing paste for minor skin infections, including boils. The whole family can benefit from Magnesium Sulfate Paste BP.

Cetavlex Cream

Cetavlex Cream

Cetavlex Cream is an antiseptic cream. It contains Cetrimide 0.5% w/w, which has shown to be active against a wide range of bacteria.

Chemists' Own Head Lice

Chemists' Own Head Lice

Repellent spray. Contains dimeticone 4%, silicone, as a head lice treatemnt.  The shampoo contains natural neem oil, eucalyptus oil, wheat proteins and margosa extract to help keep head lice at bay.

Clarelux

Clarelux

Clarelux is a very potent topical corticosteroid containing clobetasol propionate. It has anti-inflammatory, antipruritic and vasoconstrictive properties

ClearZal

ClearZal

Clear Zal is a hard skin remover cream with urea 7%, salicyclic acid, 4% and trichioroacretic acid 2%. A triple action formula which removes dead skin cells, promotes new growth with an aloe vera base for rapid absorption and increased hydration

Cocois

Cocois

Cocois is a combination of coal tar, salicylic acid and sulphur, which are widely used in the treatment of hyperkeratotic and scaling skin conditions. Coal tar is antipruritic, keratoplastic and a weak antiseptic. Salicylic acid has keratolytic properties. Sulphur is keratolytic, with weak antiseptic and parasiticide properties

Crystacide Cream 1%

Crystacide Cream 1%

Crystacide contains 1% hydrogen peroxide, which is a well-known antiseptic agent, and is effective against most pathogenic microorganisms

Curatoderm Lotion

Curatoderm Lotion

Curatoderm contains tacalcitol, a vitamin D3 derivative that inhibits keratinocyte hyper-proliferation and induces differentiation of these cells. The normalisation of these mechanisms is the basis for its efficacy in the treatment of psoriasis. In biopsies from patients treated with tacalcitol, specific indicators for inflammation were improved. Tacalcitol binds to the keratinocyte vitamin D receptor to the same extent as natural active vitamin D3.

Curatoderm Ointment

Curatoderm Ointment

Curatoderm contains tacalcitol, a vitamin D3 derivative that inhibits keratinocyte hyper-proliferation and induces differentiation of these cells. The normalisation of these mechanisms is the basis for its efficacy in the treatment of psoriasis. In biopsies from patients treated with tacalcitol, specific indicators for inflammation were improved. Tacalcitol binds to the keratinocyte vitamin D receptor to the same extent as natural active vitamin D3.

Cutivate

Cutivate

Cutivate contains fluticasone propionate which is a potent topical corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties

Daktacort

Daktacort

Daktacort is a compound of hydrocortisone and miconazole nitrate. Miconazole is a potent broad-spectrum antifungal and antibacterial agent with marked activity against dermatophytes, pathogenic yeasts (e.g. Candida spp.) and many Gram-positive bacteria, including most strains of Streptococcus and Staphylococcus. Hydocortisone is a widely used topical anti-inflammatory of value in the treatment of inflammatory skin conditions including atrophic and infantile eczema, contact sensitivity reactions and intertrigo

Daktarin

Daktarin

Daktarin contains miconazole nitrate, an imidazole antifungal agent that may act by interfering with the permeability of the fungal cell membrane. It possesses a wide antifungal spectrum and has some antibacterial activity

Dalacin T

Dalacin T

Dalacin T is an anti-infective treatment for acne. The active constituent, clindamycin, is a known antibiotic. When applied topically, it is found in comedone samples at sufficient levels to be active against most strains of Propionibacteria acnes.

Dandrazol 2% Shampoo

Dandrazol 2% Shampoo

A shampoo containing the active 2% ketoconazole, which is a type of medicine called an antifungal. It is used to treat infections with fungi and yeasts.

Dandrazol Anti-dandruff Shampoo

Dandrazol Anti-dandruff Shampoo

A shampoo containing the active 2% ketoconazole, which is a type of medicine called an antifungal. It is used to treat infections with fungi and yeasts

Derbac–M

Derbac–M

Derbac M Liquid contains malathion, a widely used organophosphorus insecticide that inhibits cholinesterase. It is effective against a wide range of insects, but is one of the least toxic organophosphorus insecticides as it is rapidly detoxified by plasma carboxylesterases

Dermacort

Dermacort

The cream formulation of Dermacort was developed in order to optimise the release and partition of its active ingredient, hydrocortisone, into the skin which is presented as a saturated or near saturated solution in aqueous propylene glycol, which represents the continuous phase of the emulsion system. It has been shown, by the vasoconstrictor assay on normal skin, that in this environment, a 0.1% concentration of the hydrocortisone is equivalent to the 1% concentration where the drug substance is in suspension. Clinical studies have confirmed that 0.1% Dermacort is equivalent to 1.0% hydrocortisone cream BP/BPC whilst the reduced strength of Dermacort increases the margin of safety.

Dermatonics Once Callus Removing Balm

Dermatonics Once Callus Removing Balm

Dermatonics Once Callus Removing Balm can be applied once or twice daily as prescribied. It combines 25% urea with ceramide rich Oat Lipd Oil and can treat callus and anhidrosis anywhere on the body. Free of parabens.

Dermax Therapeutic Shampoo

Dermax Therapeutic Shampoo

Dermax Therapeutic Shampoo contains benzalkonium chloride, which is adsorbed on to dry skin scales, these being a feature of pityriasis capitis and other seborrhoeic scalp conditions. The scales are loosened and attain a net positive charge. In the presence of the anionic foaming agent, sodium lauryl ether sulphate, the dandruff scales are then levitated into the negatively charged surface of the foam and washed from the hair. Benzalkonium chloride also acts as a mild antiseptic, which improves clinical performance when the condition is exacerbated by the presence of microbes. The major site of action against microorganisms appears to be the cell membrane, where permeability is altered

Dermovate

Dermovate

Dermovate contains clobetasol propionate, a very potent corticosteroid with topical anti-inflammatory activity. The major effect of clobetasol propionate on skin is a non-specific anti-inflammatory response, partially due to vasoconstriction and a decrease in collagen synthesis

Dermovate Scalp Application

Dermovate Scalp Application

Dermovate contains clobetasol propionate, a highly active corticosteroid with topical anti-inflammatory activity. The major effect of clobetasol propionate on skin is a non-specific anti-inflammatory response, which is partially due to vasoconstriction and decrease in collagen synthesis

Differin

Differin

Adapalene is a retinoid-like compound that has been demonstrated to have anti-inflammatory properties

Diflucan

Diflucan

Diflucan contains fluconazole, a triazole antifungal agent. Its primary mode of action is the inhibition of fungal cytochrome P-450-mediated 14 alpha-lanosterol demethylation, an essential step in fungal ergosterol biosynthesis. The accumulation of 14 alpha-methyl sterols correlates with the subsequent loss of ergosterol in the fungal cell membrane and may be responsible for the antifungal activity of fluconazole. Fluconazole has been shown to be more selective for fungal cytochrome P-450 enzymes than for various mammalian cytochrome P-450 enzyme systems

Diprosalic Ointment

Diprosalic Ointment

Diprosalic contains betamethasone dipropionate, a synthetic fluorinated corticosteroid equivalent to 0.05% betamethasone. It also contains 3% salicylic acid. It is active topically, and produces a rapid and sustained response in inflammatory dermatoses that normally respond to topical corticosteroid therapy. It is also effective in less responsive conditions, such as psoriasis of the scalp and chronic plaque psoriasis of the hands and feet, but not in widespread plaque psoriasis. Topical salicylic acid softens keratin, loosens cornified epithelium and desquamates the epidermis allowing more rapid access to the dermis than when applying steroid alone.

Diprosalic Scalp Application

Diprosalic Scalp Application

Diprosalic scalp applications contain the dipropionate ester of betamethasone, equivalent to 0.5% betamethasone, which is a glucocorticoid synthetic fluorinated corticosteroid exhibiting the general properties of corticosteroids, and 2.0% w/w salicylic acid, which has keratolytic properties. The lotion is applied topically to the scalp in the treatment of hyperkeratotic and scaling conditions, where its keratolytic action facilitates penetration of the corticosteroid.

Diprosone

Diprosone

Diprosone contains betamethasone dipropionate, a synthetic fluorinated corticosteroid equivalent to 0.05% betamethasone. It is active topically and produces a rapid and sustained response. Topical corticosteroids such as this are effective in the treatment of a range of dermatoses due to their anti-inflammatory and antipruritic actions.

Dovobet Gel

Dovobet Gel

Dovobet Gel contains a combination of calcipotriol and betamethasone dipropionate. Calcipotriol is a vitamin D analogue. In vitro data suggest that calcipotriol induces differentiation and suppresses proliferation of keratinocytes. This is the proposed basis for its effect in psoriasis. Betamethasone dipropionate is a potent topical corticosteroid with anti-inflammatory, antipruritic, vasoconstrictive and immunosuppressive properties, although it does not cure the underlying condition

Dovobet Ointment

Dovobet Ointment

Calcipotriol is a vitamin D derivative. In vitro data suggest that it induces differentiation and suppresses proliferation of keratinocytes. This is the proposed basis for its effect in psoriasis

Duac Once Daily

Duac Once Daily

Duac Once Daily gel has a combination of mild keratolytic and antibacterial properties that act  against inflamed lesions of mild to moderate acne vulgaris. Benzoyl peroxide is mildly keratolytic, acting against comedones at all stages of their development. It is an oxidising agent with bactericidal activity against Propionibacterium acnes, the organism implicated in acne vulgaris. It is also sebostatic, counteracting the excessive sebum production associated with acne. Clindamycin is a lincosamide antibiotic with bacteriostatic action against Gram-positive aerobes and a wide range of anaerobic bacteria

Duofilm

Duofilm

Duofilm is a combination of lactic and salicylic acid. Lactic acid affects the keratinisation process, reducing hyperkeratosis, which is characteristic of warts. It is caustic, which leads to the destruction of the keratotic tissue of the wart and causative virus. Salicylic acid is keratolytic, facilitating desquamation by solubilising the intercellular cement in the stratum corneum

Dysport

Dysport

Dysport is Clostridium botulinum toxin type A – Haemagglutinin complex, which blocks peripheral cholinergic transmission at the neuromuscular junction by a presynaptic action at a site proximal to the release of acetylcholine. The toxin acts within the nerve ending to antagonise those events that are triggered by Ca2+ which culminate in transmitter release. It does not affect postganglionic cholinergic transmission or postganglionic sympathetic transmission. The action of toxin involves an initial binding step whereby the toxin attaches rapidly and avidly to the presynaptic nerve membrane. Secondly, there is an internalisation step in which toxin crosses the presynaptic membrane, without causing onset of paralysis. Finally, the toxin inhibits the release of acetylcholine by disrupting the Ca2+ mediated acetylcholine release mechanism, thereby diminishing the endplate potential and causing paralysis.

Effaclar A.I. Breakout Corrector

Effaclar A.I. Breakout Corrector

Targeted breakout corrector for individual blemishes. For oily, blemish-prone skin. An
easy-to-apply, quickly absorbed, targeted SOS treatment to help reduce the appearance of localised imperfections and blemishes and prevent residual marks. Suitable for sensitive skin. Enriched with Niacinamide, Piroctone Olamine and LHA.

Efudix

Efudix

Efudix is a topical cytostatic preparation that exerts a beneficial therapeutic effect on neoplastic and pre-neoplastic skin lesions without damaging normal skin. The pattern of response follows this sequence: erythema, vesiculation, erosion, ulceration, necrosis and epithelialisation

Elidel

Elidel

Pimecrolimus is a lipophilic anti-inflammatory ascomycin macrolactam derivative and a cell selective inhibitor of the production and release of pro-inflammatory cytokines. Its skin-selective pharmacological profile is different to that of corticosteroids

Elocon

Elocon

Elocon contains mometasone furoate, which exhibits marked anti-inflammatory and anti-psoriatic activity

Enstilar Cutaneous Foam

Enstilar Cutaneous Foam

The active ingredients in Enstilar Cutaneous Foam are calcipotriol (as monohydrate) and betamethasone (as dipropionate). Enstilar contains a combination of calcipotriol and betamethasone dipropionate. Calcipotriol is a vitamin D analogue. In vitro data suggest that calcipotriol induces differentiation and suppresses proliferation of keratinocytes. This is the proposed basis for its effect in psoriasis. Betamethasone dipropionate is a potent topical corticosteroid with anti-inflammatory, antipruritic, vasoconstrictive and immunosuppressive properties, although it does not cure the underlying condition.

Epiduo Gel

Epiduo Gel

Epiduo contains a combination of adapalene and benzoyl peroxide. Adapalene is a retinoid-like compound that is a potent modulator of cellular differentiation and keratinisation and has anti-inflammatory properties. This profile suggests that the cell-mediated inflammatory component of acne is reduced by adapalene. Benzoyl peroxide has been shown to have antimicrobial activity, particularly against Propionibacterium acnes, which is abnormally present in the acne-affected pilosebaceous unit. In addition, benzoyl peroxide has demonstrated exfoliative and keratolytic activities and is sebostatic, counteracting the excessive sebum production associated with acne

Etrivex

Etrivex

Etrivex contains clobetasol propionate, which has anti-inflammatory, antipruritic, and vasoconstrictive properties. It is a short contact formulation to be applied for 15 minutes to a dry scalp. After this time add water, lather and rinse the product completely off the scalp

Eucerin Dermo Capillaire Scalp Treatment with 5% urea

Eucerin Dermo Capillaire Scalp Treatment with 5% urea

Provides an intensive moisturising and calming effect for a dry and itchy scalp with 5% urea and lactate to help reduce moisture loss. Also contains licorice extract and polidocanol to soothe and reduce itchiness

Eumovate

Eumovate

Clobetasone butyrate is a moderately potent topical corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of steroid responsive dermatoses

Eurax HC Cream

Eurax HC Cream

Eurax HC Cream's dual action formula works to provide fast relief from itching that lasts up to 10 hours, while also reducing inflammation and swelling.

Exorex Lotion 5% v/w Cutaneous Emulsion

Exorex Lotion 5% v/w Cutaneous Emulsion

Exorex Lotion contains coal tar, an antipruritic and keratoplastic. It is a patented formulation containing the active ingredient coal tar solution (5% v/w) in a base containing a complex of esterified essential fatty acids. Tar acids have also been shown to have disinfectant properties. Exorex Lotion may be used alone, or as part of a more extensive treatment regimen

Fenistil Cold Sore Cream

Fenistil Cold Sore Cream

Fenistil contains penciclovir, which has demonstrable in vivo and in vitro activity against herpes simplex viruses (types 1 and 2) and varicella zoster virus. In virus-infected cells penciclovir is rapidly and efficiently converted into a triphosphate (mediated via virus-induced thymidine kinase)

Finacea

Finacea

Finacea contains azelaic acid, an antimicrobial that has a direct effect on follicular hyperkeratosis as a therapy for acne

Fludroxycortide Cream

Fludroxycortide Cream

Fludroxycortide Cream and Ointment (formally Haelan cream and Ointment) contains fludroxycortide, a fluorinated synthetic moderately potent topical corticosteroid. As with other topical steroids, the therapeutic effect is primarily the result of its anti-inflammatory activities.

Fucibet Cream

Fucibet Cream

Fucibet Cream combines the well-known anti-inflammatory and antipruritic effects of betamethasone with the topical antibacterial action of fusidic acid. Betamethasone valerate is a topical steroid that is rapidly effective in inflammatory dermatoses that normally respond to this form of therapy. More refractory conditions can often be treated successfully. When applied topically, fusidic acid is effective against Staphylococcus aureus, Streptococcus, Corynebacterium, Neisseria and certain clostridia and Bacteroides. Concentrations of 0.03-0.12µg per ml inhibit nearly all strains of S. aureus. The antibacterial activity of fusidic acid is not diminished in the presence of betamethasone

Fucibet Lipid Cream

Fucibet Lipid Cream

Fucibet Lipid Cream combines the well-known anti-inflammatory and antipruritic effects of betamethasone with the topical antibacterial action of fusidic acid. Betamethasone valerate is a topical steroid that is rapidly effective in inflammatory dermatoses that normally respond to this form of therapy. More refractory conditions can often be treated successfully. When applied topically, fusidic acid is effective against Staphylococcus aureus, Streptococcus, Corynebacterium, Neisseria and certain clostridia and Bacteroides. Concentrations of 0.03-0.12µg per ml inhibit nearly all strains of S. aureus. The antibacterial activity of fusidic acid is not diminished in the presence of betamethasone

Fucidin

Fucidin

Fucidin contains fusidic acid, a potent antibacterial agent. Fusidic acid and its salts show fat and water solubility and strong surface activity, and exhibit an unusual ability to penetrate intact skin. Concentrations of 0.03–0.12mcg fusidic acid per ml inhibit nearly all strains of Staphylococcus aureus. Topical application is also effective against streptococci, corynebacteria, niesseria and certain clostridia

Fucidin H Cream

Fucidin H Cream

Fucidin H Cream combines the potent topical antibacterial action of fusidic acid with the anti-inflammatory and antipruritic effects of hydrocortisone. Concentrations of 0.03–0.12µg/ml of fusidic acid inhibit nearly all strains of Staphylococcus aureus. Topical application of fusidic acid is also effective against Streptococcus, Corynebacterium, Neisseria and certain clostridia

Full Marks

Full Marks

Full Marks contains isopropyl myristate and cyclomethicone. It is a thin, oily liquid, which spreads quickly and completely through the hair to saturate the scalp and kill head lice and eliminate their eggs. Using the fine-tooth metal comb provided, the solution is then combed through the hair once the required time has elapsed

Glutarol

Glutarol

Glutarol contains glutaraldehyde, a virucidal that inactivates the wart virus. On the skin, it also acts as an anhidrotic, drying the warts and surrounding skin, thus reducing the spread of lesions and simplifying the removal of persistent warts by curettage

Grisol AF Spray

Grisol AF Spray

Grisol AF scuntaneous spray contains 1% w/w griseofulvin, which is an anti-fungal treatment for infections with fungi and yeasts. Each spray delivers 400µg of griseofulvin (0.05ml per dose)

Grisol Spray

Grisol Spray

Grisol AF scuntaneous spray contains 1% w/w griseofulvin, which is an antifungal treatment for infections with fungi and yeasts. Each spray delivers 400µg of griseofulvin (0.05ml per dose)

 

 

Hedrin

Hedrin

Hedrin solution contains dimeticone, which is used in many pharmaceutical and cosmetic preparations. A 4% concentration has been found to affect the physico-physiological activity of lice. It is less effective in its ovicidal activity and therefore two applications, 7 days apart, are required. It contains no neurotoxic organophosphate insecticides and acts by a physical process that covers the lice and disrupts their ability to manage their water balance so that treated insects fail to excrete surplus water. Its activity is not diminished in insecticide-resistant head lice

Lamisil AT Gel

Lamisil AT Gel

Lamisil contains terbinafine, an allylamine which has a broad spectrum of antifungal activity. At low concentrations terbinafine is fungicidal against dermatophytes, moulds and certain dimorphic fungi. Its activity against yeasts is fungicidal or fungistatic, depending on the species. Terbinafine interferes specifically with fungal sterol biosynthesis at an early step. This leads to a deficiency in ergosterol and an intracellular accumulation of squalene, resulting in fungal cell death.

Lamisil AT Spray

Lamisil AT Spray

Lamisil contains terbinafine, an allylamine which has a broad spectrum of antifungal activity. At low concentrations terbinafine is fungicidal against dermatophytes, moulds and certain dimorphic fungi. Its activity against yeasts is fungicidal or fungistatic, depending on the species. Terbinafine interferes specifically with fungal sterol biosynthesis at an early step. This leads to a deficiency in ergosterol and an intracellular accumulation of squalene, resulting in fungal cell death

Lamisil Once cutaneous solution

Lamisil Once cutaneous solution

Lamisil contains terbinafine, an allylamine which has a broad spectrum of antifungal activity. At low concentrations terbinafine is fungicidal against dermatophytes, moulds and certain dimorphic fungi. Its activity against yeasts is fungicidal or fungistatic, depending on the species. Terbinafine interferes specifically with fungal sterol biosynthesis at an early step. This leads to a deficiency in ergosterol and an intracellular accumulation of squalene, resulting in fungal cell death

Loceryl

Loceryl

Loceryl is a topical antimycotic that contains amorolfine belonging to a new chemical class its fungicidal action is based on an alteration of the fungal cell membrane, targeted primarily on sterol biosynthesis. The ergosterol content is reduced, and at the same time unusual sterically non-planar sterols accumulate. Amorolfine is a broad-spectrum antimycotic. It is highly active against yeast, dermatophytes, moulds, dermatiacea and dimorphic fungi

Locoid

Locoid

Locoid contains hydrocortisone butyrate, which is a potent topical corticosteroid; 0.1% w/w hydrocortisone butyrate. Locoid Scalp Lotion contains 0.1% hydrocortisone butyrate, a potent topical corticosteroid

Lotriderm

Lotriderm

Lotriderm Cream contains the dipropionate ester of betamethasone, a glucocorticoid exhibiting the general properties of corticosteroids, and clotrimazole, which is an imidazole antifungal agent.

Lyclear

Lyclear

Lyclear contains permethrin, which belongs to a group of anti-parasitic agents called pyrethroids. Permethrin is rapidly absorbed across the insect cuticle. The principal physiological action is the induction of electrochemical abnormalities across the membranes of excitable cells, leading to sensory hyperexcitability, incoordination and prostration. When presented in an aqueous base, the ovicidal activity of permethrin is increased by the addition of an alcohol

Lypsyl Cold Sore Gel

Lypsyl Cold Sore Gel

Lypsyl Cold Sore Gel contains lidocaine hydrochloride, cetrimide and zinc sulphate. Lidocaine hydrochloride produces surface anaesthesia. Cetrimide has emulsifying and detergent properties. Zinc sulphate has astringent properties

Metosyn

Metosyn

Metosyn contains fluocinonide, which is a synthetic anti-inflammatory corticosteroid. Its mechanism of action is related to vasoconstriction and suppression of membrane permeability, miototic activity, the immune response and release of inflammatory mediators

Metrogel

Metrogel

Metrogel contains 0.75% metronidazole, which is a topical antibacterial

Metvix Cream

Metvix Cream

After topical application of Metvix (methyl aminolevulinate), porphyrins accumulate intracellularly in the treated skin lesions. The intracellular porphyrins (including PplX) are photoactive, fluorescing compounds and, on light activation in the presence of oxygen, singlet oxygen is formed, which causes damage to cellular compartments, in particular the mitochondria. Light activation of accumulated porphyrins leads to a photochemical reaction and thereby phototoxicity to the light-exposed target cells

Mildison Lipocream

Mildison Lipocream

Mildison contains hydrocortisone and has the pharmacological actions of a corticosteroid classified as mildly potent. Strength i.e.1% w/w hydrocortisone.

Mirvaso

Mirvaso

Brimonidine is a highly selective alpha2-adrenergic receptor agonist that is 1000-fold more selective for the alpha2-adrenergic receptor than the alpha1-adrenergic receptor.

Cutaneous facial application of a highly selective alpha2-adrenergic receptor agonist reduces erythema through direct cutaneous vasoconstriction.

MolluDab

MolluDab

MolluDab is used externally against molluscum contagiosum, a skin lesion caused by a virus. MolluDab causes cells which are affected by the virus to dissolve and thereby produces a defence reaction of the skin in the region affected by molluscum contagiosum

Molutrex

Molutrex

Molutrex contains a stable solution of potassium hydroxide (also known as KOH). This agent breaks down the hard keratin surface of the skin. When painted onto the molluscum blisters this sets off an irritant reaction which stimulates the body's own immune system to attack the virus. The virus is destroyed and the blisters heal.

Mycota

Mycota

An SLS free, 2-in-1 leave on emollient and wash that adds moisture to the skin for the relief of flaking dry skin conditions.

Neutrogena T/Gel

Neutrogena T/Gel

NeutrogenaT/GelTherapeutic Shampoo is a fragranced medicated shampoo for the treatment of itchy, flaky scalp disorders. Regular use helps to control these problems, while treating the scalp and caring for your hair. Treatment usually lasts for 6 weeks, after which time improvement should be seen. Longer periods of treatment should only take place under the supervision of a doctor. Active ingredients: Neutar 2% solubilised coal tar extract 20mg/ml

Nicam Gel

Nicam Gel

Niacin (nicotinic acid) is an essential B complex vitamin (B3). Nicotinamide (niacinamide) is the physiologically active form of niacin and has been shown to have beneficial effects on inflammatory acne. It is considered that these effects are related to its significant anti-inflammatory activity

Nizoral

Nizoral

Nizoral contains ketoconazole, which has a potent antimycotic action against dermatophytes and yeasts. Ketoconazole cream acts rapidly on pruritus, which is commonly seen in dermatophyte and yeast infections

Nizoral Anti-dandruff Shampoo

Nizoral Anti-dandruff Shampoo

Nizoral with Ketoconazole combats the fungus that causes dandruff and quickly relieves from itching and flaking. Clinically proven to control itching and flaking. For freedom from dandruff (treatment and prevention). Starts working from the first hair wash. Can give visible results in 2 weeks.

Nystatin

Nystatin

Nystatin (formally Nystaform) contains a combination of nystatin and chlorhexidine. Nystatin is a fungistatic and fungicidal antibiotic, primarily effective against Candida albicans.  Chlorhexidine is active against a wide range of bacteria

Nystatin HC

Nystatin HC

Nystatin HC (formally Nystaform HC) contains a combination of nystatin, chlorhexidine and hydrocortisone. Nystatin is a fungistatic and fungicidal antibiotic that is primarily effective against Candida albicans. Chlorhexidine is effective against a wide range of bacteria. Hydrocortisone exercises a vasoconstrictive effect, thus reducing inflammation and oedema, and has an antipruritic effect

Occlusal

Occlusal

Occlusal contains salicylic acid, which has bacteriostatic and fungicidal actions, but its keratolytic properties are important for this product. When applied externally, it produces slow and painless destruction of the epithelium

Otezla

Otezla

Apremilast, an oral small-molecule inhibitor of phosphodiesterase 4 (PDE4), works intracellularly to modulate a network of pro-inflammatory and anti-inflammatory mediators. PDE4 is a cyclic adenosine monophosphate (cAMP)-specific PDE and the dominant PDE in inflammatory cells. PDE4 inhibition elevates intracellular cAMP levels, which in turn down-regulates the inflammatory response by modulating the expression of TNF-α, IL-23, IL-17 and other inflammatory cytokines. Cyclic AMP also modulates levels of anti-inflammatory cytokines such as IL-10. These pro- and anti-inflammatory mediators have been implicated in psoriatic arthritis and psoriasis.

Permethrin 5% Cream

Permethrin 5% Cream

Permethrin induces electrochemical abnormalities across the membranes of the excitable cells of susceptible parasites. This leads to sensory hyper-excitability, lack of coordination and prostration.

Perspi-Guard Maximum Strength Antiperspirant

Perspi-Guard Maximum Strength Antiperspirant

A topical solution for hyperhidrosis (excessive sweating). It offers protection from both sweat and odour, while remaining gentle on the skin. Containing aluminum chloride and aluminum chlorohydrate, the concentrated formulation requires application once or twice per week. 

Perspi-Guard Odour Control Bodywash

Perspi-Guard Odour Control Bodywash

This body wash has been formulated to treat bromhidrosis (malodorous sweating) by cleansing the skin and eliminating body odours from commonly affected problem areas, such as underarms, feet and groin. It contains Triclosan, which targets and reduces the odour-causing bacteria that build up on the skin during sweating

Pevaryl

Pevaryl

Pevaryl contains econazole nitrate, which is a broad-spectrum antimycotic with activity against dermatophytes, yeasts and moulds. A clinically relevant action against Gram-positive bacteria has also been found

Picato

Picato

The active ingredient in Picato gel is ingenol mebutate

Pickles

Pickles

Pickles is a 50% salicylic acid ointment, which should be used with a corn ring to protect surrounding skin.

Protopic

Protopic

The mechanism of action of tacrolimus in atopic dermatitis is not fully understood. While the following have been observed, the clinical significance of these observations in atopic dermatitis is not known. Via its binding to a specific cytoplasmic immunophilin (FKBP12), tacrolimus inhibits calcium-dependent signal transduction pathways in T cells, thereby preventing the transcription and synthesis of IL-2, IL-3, IL-4, IL-5 and other cytokines such as GM-CSF, TNFα and IFNγ. In patients with atopic dermatitis, improvement of skin lesions during treatment with tacrolimus ointment was associated with reduced Fc receptor expression on Langerhans cells and a reduction of their hyperstimulatory activity towards T cells. Tacrolimus ointment does not affect collagen synthesis in humans

Psoriderm Cream

Psoriderm Cream

Psoriderm Cream is a coal tar preparation. Coal tar has been used dermatologically for hundreds of years and has been shown to be safe and effective in the treatment of scaly skin conditions such as psoriasis. The precise mechanism of action of coal tar is not understood, largely as a result of it comprising up to 10,000 components. There is evidence that topical application of coal tar improves psoriasis by reducing the excessive rate of mitotic epidermal cell division.

Psoriderm Scalp Lotion

Psoriderm Scalp Lotion

Psoriderm Scalp Lotion is a coal tar shampoo preparation. Coal tar has been used dermatologically for hundreds of years and has been shown to be safe and effective in the treatment of scaly skin conditions such as psoriasis. The precise mechanism of action of coal tar is not understood, largely as a result of it comprising up to 10, 000 components. There is evidence that topical application of coal tar improves psoriasis by reducing the excessive rate of mitotic epidermal cell division.

Psorin

Psorin

Psorin contains dithranol and coal tar; both suppress the proliferation of psoriatic tissue. Salicylic acid acts as a keratolytic. The emollient base helps to promote healing of psoriatic areas

Quinoderm Cream /Quinoderm Cream 5

Quinoderm Cream /Quinoderm Cream 5

Quinoderm contains a combination of the mild keratolytic properties of benzoyl peroxide and the antibacterial and antifungal properties of potassium hydroxyquinoline sulfate in a specially formulated bland water-miscible base. 

Regaine

Regaine

Regaine for Men Extra Strength Scalp Foam 5% w/w Minoxidil and Solution contain 5% of the active ingredient, minoxidil. Regaine for Women contains 2% minoxidil. The mechanism by which minoxidil stimulates hair growth is not fully understood, but it can reverse the hair-loss process of androgenetic alopecia by the following means: increasing the diameter of the hair shaft, stimulating anagen growth, prolonging the anagen phase, and stimulating anagen recovery from the telegon phase. A peripheral vasodilator, minoxidil enhances microcirculation to hair follicles. It also stimulates expression of vascular endothelial growth factor (VEGF), which is indicative of the high metabolic activity observed during the anagen phase

Rosalic AR Intense

Rosalic AR Intense

Intensive care for skin prone to redness, discomfort and skin tone changes. Targets skin tone irregularity and helps to prevent its reappearance. Helps comfort the look of red skin

Rosiced

Rosiced

Rosiced contains 0.75% metronidazole which is active against the inflammatory aspect of rosacea. Metronidazole belongs to the group of nitroimidazoles. It is reduced in sensitive protozoa and strictly anaerobic bacteria with formation of acetamide and N-(2-hydroxyethyl)-oxamid acid. Interaction with DNA leads to inhibition of the nucleic acid synthesis of the microorganisms concerned, which results in the death of these agents

Rozex

Rozex

Rozex contains 0.75% metroniazole, an antiprotozoal and antibacterial agent that is active against a wide range of pathogenic microorganisms. The mechanisms of action of metronidazole in rosacea are unknown, but evidence suggests that the effects may be antibacterial and/or anti-inflammatory

Salactol

Salactol

Salactol is a combination of salicylic acid and lactic acid in flexible collodion. Salicylic acid has bacteriostatic and fungicidal actions, as well as keratolytic properties. Its effectiveness as a topical treatment for hyperkeratotic skin lesions is based on its mild keratolytic action, which slowly and painlessly destroys the epithelium. In the treatment of warts, a mild irritant reaction, which may render the virus more prone to immunologic stimulation or response, may add to the mechanical removal of infected cells. In addition to its antiseptic and caustic properties, lactic acid enhances the availability of salicylic acid from the dried collodion

Salatac Gel

Salatac Gel

Salatac Gel is a combination of salicylic acid and lactic acid, which are routinely used in the treatment of verrucas, warts, corns and calluses for their keratolytic properties. When applied topically and in high enough concentrations, salicylic acid acts by achieving a slow, painless destruction of the thickened stratum corneum. It softens and destroys the stratum corneum of the affected tissue by reducing the adhesiveness of the corneocytes while causing the cornified epithelium to swell, soften, macerate and finally desquamate. In the treatment of warts, a mild irritant reaction, which may render the virus more prone to immunologic stimulation or response, may add to the mechanical removal of infected cells. In addition to its antiseptic and caustic properties, lactic acid enhances the availability of salicylic acid from the dried collodion

Sebco

Sebco

An ointment containing coal tar solution 12% w/w, salicylic acid 2% w/w and sulfur for external use 4% w/w in a coconut oil base. The mixture of coal tar, salicylic acid and sulfur reduces itch, helps remove scaly skin and has antiseptic properties. Sebco is used in the treatment of skin diseases which cause dry scaly skin on the scalp. These include psoriasis, eczema, seborrhoeic dermatitis and dandruff. It has mild antipruritic, antiseptic and keratolytic properties and is based on an ointment called Unguentum Cocois Co.

Selsun

Selsun

Selsun shampoo contains 2.5% selenium sulphide, which appears to have a cytostatic effect on cells of the epidermis and follicular epithelium, reducing corneocyte production. Selsun acts as an anti-seborrhoeic agent which effectively controls itching and scaling dandruff. It is active against certain dermatophytes, including Pityrosporum orbiculare, the organism causing pityriasis versicolor (tinea versicolor)

Silkis

Silkis

Silkis contains calcitriol which inhibits the proliferation and stimulates differentiation of keratinocytes. Calcitriol inhibits proliferation of T cells and normalises the production of various inflammation factors

Skinoren

Skinoren

Skinoren contains azelaic acid, which inhibits the growth of the Propionibacteria involved in the development of acne and the production of acne-promoting fatty acids. Azelaic acid also reduces the multiplication and keratinisation of keratinocytes, and therefore restricts the formation of comedones.

Solaraze

Solaraze

Solaraze contains diclofenac, a non-steroidal anti-inflammatory. The mechanism of action of diclofenac in actinic keratosis is not known but may be related to the inhibition of the cycloxygenase pathway leading to reduced prostaglandin E2 (PGE2) synthesis

Soolantra

Soolantra

Ivermectin is a member of the avermectin class. Avermectin has anti-inflammatory effects by inhibiting lipopolysaccharide-induced production of inflammatory cytokines. Anti-inflammatory properties of cutaneous ivermectin have been observed in animal models of skin inflammation. Ivermectin also causes death of parasites, primarily through binding selectively and with high affinity to glutamate-gated chloride channels, which occur in invertebrate nerve and muscle cells. The mechanism of action of Soolantra in treating the inflammatory lesions of rosacea is not known but may be linked to anti-inflammatory effects of ivermectin as well as causing the death of Demodex mites that have been reported to be a factor in inflammation of the skin

Synalar

Synalar

Synalar contains fluocinolone acetonide, which is a synthetic anti-inflammatory corticosteroid. Its mechanism of action is related to vasoconstriction and suppression of membrane permeability, miotic activity, the immune response and release of inflammatory mediators

Synalar 1 in 4 Dilution

Synalar 1 in 4 Dilution

Synalar contains fluocinolone acetonide, a synthetic anti-inflammatory corticosteroid prepared as a 1 in 4 dilution. Its mechanism of action is related to vasoconstriction and suppression of membrane permeability, miotic activity, the immune response and release of inflammatory mediators

Synalar C

Synalar C

Synalar contains fluocinolone acetonide (a synthetic anti-inflammatory corticosteroid), and clioquinol (a broad-spectrum antifungal and antibacterial agent). Its mechanism of action is related to vasoconstriction and suppression of membrane permeability, miotic activity, the immune response and release of inflammatory mediators

Synalar N

Synalar N

Synalar contains fluocinolone acetonide (a synthetic anti-inflammatory corticosteroid), and neomycin (a broad-spectrum antifungal and antibacterial agent). Its mechanism of action is related to vasoconstriction and suppression of membrane permeability, miotic activity, the immune response and release of inflammatory mediators

Terra-Cortril Ointment

Terra-Cortril Ointment

Terra-Cortril Ointment possesses both the anti-inflammatory activity of 1% hydrocortisone and the broad-spectrum antibacterial activity of 3% oxytetracycline, which is active against a wide variety of Gram-positive and Gram-negative organisms

Timodine

Timodine

For the treatment of dermatoses, including intertrigo, eczema, seborrhoeic dermatitis, atopic dermatitis, and pruritis ani et vulvae, in which infection with Candida albicans is a factor. For the treatment of severe nappy rash in which infection with C. albicans is a factor

Treclin

Treclin

Treclin is a combination therapy of clindamycin and tretinoin. Clindamycin is a semisynthetic derivative of the parent compound lincomycin that is produced by Streptomyces lincolnensis and is predominantly bacteriostatic. Topical tretinoin has both comedolytic and anti-inflammatory effects. Tretinoin decreases cohesiveness of follicular epithelial cells resulting in decreased microcomedone formation. Additionally, tretinoin stimulates mitotic activity and increased turnover of follicular epithelial cells, causing extrusion of the comedones.

Trimovate

Trimovate

Trimovate contains clobetasone butyrate, a topically active corticosteroid, combined with antibiotics (nystatin and oxytetracycline), providing a broad spectrum of antibacterial and anti-candidal activity against many of the organisms associated with infected dermatoses

Trosyl Nail solution

Trosyl Nail solution

Tioconazole is an imidazole that is active against commonly occurring dermatophyte and yeast-like fungal species. It is fungicidal in murine models vs Candida spp., T. rubrum and T. mentacrophytes. In vitro, it is fungicidal to pathenogenic dermatophytes, yeasts and other fungi

UCS Debridement

UCS Debridement

A sterile, pre-moistened, single-use cloth for effective wound debridement and cleansing of the surrounding leg area. The soft debridement cloth contains a mild cleansing solution that moisturises and softens without damaging healthy cells.

Ultralanum

Ultralanum

Ultralanum plain cream and ointment both contain the active ingredient fluocortolone, which is a type of medicine known as a topical corticosteroid.

Corticosteroids are medicines used for reducing inflammation.

When fluocortolone is applied to the skin it works by acting inside the skin cells to decrease the release of these inflammatory substances. This reduces swelling, redness and itch.

Vamousse

Vamousse

Contains isopropyl alcohol 1.5%, benzyl alcohol 1.5% and is a quick-acting head lice treatment which kills lice and eggs within 15 minutes of contact.

Vaniqa

Vaniqa

Vaniqa contains elornithine, which irreversibly inhibits ornithine decarboxylase, an enzyme involved in the production of the hair shaft by the hair follicle. Vaniqa has been shown to reduce the rate of hair growth.

Verrugon

Verrugon

Verrugon contains the active ingredient salicylic acid, which is a keratolytic. Salicylic acid works by breaking down keratin, a protein that forms part of the skin structure. This results in the shedding of skin cells from the affected area. In the treatment of verrucas, the effect of salicylic acid is to remove the affected skin over a period of time. If successful, the new skin that grows underneath will be healthy

Zineryt

Zineryt

Zineryt contains a combination of erythromycin and zinc. Erythromycin is known to be efficacious, at 4%, in the topical treatment of acne vulgaris. The topical use of zinc is established as an aid to wound healing. The zinc acetate is solubilised by complexing with the erythromycin, and delivery is enhanced by the chosen vehicle.

Zorac

Zorac

Tazarotene, a member of the acetylenic class of retinoids, is a prodrug that is converted to its active free form, tazarotenic acid, by de-esterification in the skin area. The exact mechanism of action in psoriasis is, as yet, unknown. Improvement in patients with psoriasis occurs in association with restoration of normal cutaneous morphology, and reduction of the inflammatory markers ICAM 1 and HLA DR, and of markers of epidermal hyperplasia and abnormal differentiation, such as elevated keratinocyte transglutaminase, involucrin and keratin 16

Zovirax

Zovirax

Zovirax contains aciclovir, which is an antiviral agent that is highly active in vitro against herpes simplex virus (HSV) types I and II and varicella zoster virus (including initial and recurrent genital herpes and herpes labialis)

Zyclara

Zyclara

Imiquimod is an immune response modifier. It is the lead compound of the imidazoline family. Zyclara contains 3.75% imiquimod

Zyomet

Zyomet

Zyomet is a 0.75% metronidazole gel. Metronidazole is an antiprotozoal and antibacterial agent, which is active against a wide range of pathogenic microorganisms. The mechanisms of action of metronidazole in rosacea are unknown but evidence suggests that the effects may be antibacterial and/or anti-inflammatory.