Dermatology Handbook

The professional's guide to product selection

Psoriasis treatments

Bettamousse

Bettamousse

Bettamousse contains betamethasone, a glucocorticosteroid that has topical anti-inflammatory activity. Bettamousse is used for the treatment of steroid-responsive dermatoses of the scalp, such as psoriasis. Topical application by massaging into the affected areas. Contains betamethasone valerate, a glucocorticosteroid which has topical anti-inflammatory activity.

Calcipotriol 50 micrograms/ml Ointment

Calcipotriol 50 micrograms/ml Ointment

Calcipotriol is a vitamin D derivative. In vitro data show that calcipotriol induces differentiation and suppresses proliferation of keratinocytes. The effect of calcipotriol in psoriasis is ascribed mainly to this. 

Calcipotriol 50 micrograms/ml Scalp Solution

Calcipotriol 50 micrograms/ml Scalp Solution

Calcipotriol is a vitamin D derivative. In vitro data show that calcipotriol induces differentiation and suppresses proliferation of keratinocytes. The effect of calcipotriol in psoriasis is ascribed mainly to this. 

Cocois

Cocois

Cocois is a combination of coal tar, salicylic acid and sulphur, which are widely used in the treatment of hyperkeratotic and scaling skin conditions. Coal tar is antipruritic, keratoplastic and a weak antiseptic. Salicylic acid has keratolytic properties. Sulphur is keratolytic, with weak antiseptic and parasiticide properties

Curatoderm Lotion

Curatoderm Lotion

Curatoderm contains tacalcitol, a vitamin D3 derivative that inhibits keratinocyte hyper-proliferation and induces differentiation of these cells. The normalisation of these mechanisms is the basis for its efficacy in the treatment of psoriasis. In biopsies from patients treated with tacalcitol, specific indicators for inflammation were improved. Tacalcitol binds to the keratinocyte vitamin D receptor to the same extent as natural active vitamin D3.

Curatoderm Ointment

Curatoderm Ointment

Curatoderm contains tacalcitol, a vitamin D3 derivative that inhibits keratinocyte hyper-proliferation and induces differentiation of these cells. The normalisation of these mechanisms is the basis for its efficacy in the treatment of psoriasis. In biopsies from patients treated with tacalcitol, specific indicators for inflammation were improved. Tacalcitol binds to the keratinocyte vitamin D receptor to the same extent as natural active vitamin D3.

Dovobet Gel

Dovobet Gel

Dovobet Gel contains a combination of calcipotriol and betamethasone dipropionate. Calcipotriol is a vitamin D analogue. In vitro data suggest that calcipotriol induces differentiation and suppresses proliferation of keratinocytes. This is the proposed basis for its effect in psoriasis. Betamethasone dipropionate is a potent topical corticosteroid with anti-inflammatory, antipruritic, vasoconstrictive and immunosuppressive properties, although it does not cure the underlying condition

Dovobet Ointment

Dovobet Ointment

Calcipotriol is a vitamin D derivative. In vitro data suggest that it induces differentiation and suppresses proliferation of keratinocytes. This is the proposed basis for its effect in psoriasis

Enstilar Cutaneous Foam

Enstilar Cutaneous Foam

The active ingredients in Enstilar Cutaneous Foam are calcipotriol (as monohydrate) and betamethasone (as dipropionate). Enstilar contains a combination of calcipotriol and betamethasone dipropionate. Calcipotriol is a vitamin D analogue. In vitro data suggest that calcipotriol induces differentiation and suppresses proliferation of keratinocytes. This is the proposed basis for its effect in psoriasis. Betamethasone dipropionate is a potent topical corticosteroid with anti-inflammatory, antipruritic, vasoconstrictive and immunosuppressive properties, although it does not cure the underlying condition.

Etrivex

Etrivex

Etrivex contains clobetasol propionate, which has anti-inflammatory, antipruritic, and vasoconstrictive properties. It is a short contact formulation to be applied for 15 minutes to a dry scalp. After this time add water, lather and rinse the product completely off the scalp

Eucerin Dermo Capillaire Scalp Treatment with 5% urea

Eucerin Dermo Capillaire Scalp Treatment with 5% urea

Provides an intensive moisturising and calming effect for a dry and itchy scalp with 5% urea and lactate to help reduce moisture loss. Also contains licorice extract and polidocanol to soothe and reduce itchiness

Exorex Lotion 5% v/w Cutaneous Emulsion

Exorex Lotion 5% v/w Cutaneous Emulsion

Exorex Lotion contains coal tar, an antipruritic and keratoplastic. It is a patented formulation containing the active ingredient coal tar solution (5% v/w) in a base containing a complex of esterified essential fatty acids. Tar acids have also been shown to have disinfectant properties. Exorex Lotion may be used alone, or as part of a more extensive treatment regimen

Psoriderm Cream

Psoriderm Cream

Psoriderm Cream is a coal tar preparation. Coal tar has been used dermatologically for hundreds of years and has been shown to be safe and effective in the treatment of scaly skin conditions such as psoriasis. The precise mechanism of action of coal tar is not understood, largely as a result of it comprising up to 10,000 components. There is evidence that topical application of coal tar improves psoriasis by reducing the excessive rate of mitotic epidermal cell division.

Psoriderm Scalp Lotion

Psoriderm Scalp Lotion

Psoriderm Scalp Lotion is a coal tar shampoo preparation. Coal tar has been used dermatologically for hundreds of years and has been shown to be safe and effective in the treatment of scaly skin conditions such as psoriasis. The precise mechanism of action of coal tar is not understood, largely as a result of it comprising up to 10, 000 components. There is evidence that topical application of coal tar improves psoriasis by reducing the excessive rate of mitotic epidermal cell division.

Psorin

Psorin

Psorin contains dithranol and coal tar; both suppress the proliferation of psoriatic tissue. Salicylic acid acts as a keratolytic. The emollient base helps to promote healing of psoriatic areas

Sebco

Sebco

An ointment containing coal tar solution 12% w/w, salicylic acid 2% w/w and sulfur for external use 4% w/w in a coconut oil base. The mixture of coal tar, salicylic acid and sulfur reduces itch, helps remove scaly skin and has antiseptic properties. Sebco is used in the treatment of skin diseases which cause dry scaly skin on the scalp. These include psoriasis, eczema, seborrhoeic dermatitis and dandruff. It has mild antipruritic, antiseptic and keratolytic properties and is based on an ointment called Unguentum Cocois Co.

Silkis

Silkis

Silkis contains calcitriol which inhibits the proliferation and stimulates differentiation of keratinocytes. Calcitriol inhibits proliferation of T cells and normalises the production of various inflammation factors

Zorac

Zorac

Tazarotene, a member of the acetylenic class of retinoids, is a prodrug that is converted to its active free form, tazarotenic acid, by de-esterification in the skin area. The exact mechanism of action in psoriasis is, as yet, unknown. Improvement in patients with psoriasis occurs in association with restoration of normal cutaneous morphology, and reduction of the inflammatory markers ICAM 1 and HLA DR, and of markers of epidermal hyperplasia and abnormal differentiation, such as elevated keratinocyte transglutaminase, involucrin and keratin 16