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Zorac

Allergan Ltd

DESCRIPTION

Tazarotene, a member of the acetylenic class of retinoids, is a prodrug that is converted to its active free form, tazarotenic acid, by de-esterification in the skin area. The exact mechanism of action in psoriasis is, as yet, unknown. Improvement in patients with psoriasis occurs in association with restoration of normal cutaneous morphology, and reduction of the inflammatory markers ICAM 1 and HLA DR, and of markers of epidermal hyperplasia and abnormal differentiation, such as elevated keratinocyte transglutaminase, involucrin and keratin 16

INDICATIONS

For the topical treatment of mild to moderate plaque psoriasis involving up to 10% body surface area. Available in two concentrations. To initiate a treatment, it is advisable to start with 0.05% concentration in order to evaluate the skin response and tolerance before progressing to 0.1% if necessary

PREPARATIONS AVAILABLE

Gel

SIZES AVAILABLE

30g (0.05% and 0.1%)

PRICE

£14.09 – 0.05%, £14.80 – 0.1%