Dovobet Gel

Contains calcipotriol and betamethasone. Calcipotriol is a vitamin D analogue. One gram of ointment contains 50 micrograms of calcipotriol and 0.5 mg of betamethasone (as 0.643 mg betamethasone dipropionate). One gram of ointment contains 50 micrograms of butylhydroxytoluene (E321).

Dalonev is a calcipotriol/ betamethasone combination. Calcipotriol is a vitamin D analogue. In vitro data suggest that calcipotriol induces differentiation and suppresses proliferation of keratinocytes. This is the proposed basis for its effect in psoriasis.Like other topical corticosteroids, betamethasone dipropionate has anti-inflammatory, antipruritic, vasoconstrictive and immunosuppressive properties, however, without curing the underlying condition. Through occlusion the effect can be enhanced due to increased penetration of the stratum corneum. The incidence of adverse events will increase because of this. In general, the mechanism of the anti-inflammatory activity of the topical steroids is unclear. DRetinoid X Receptor (RXR) activity). In addition, trifarotene modulates retinoid target genes (differentiation and inflammatory processes) in immortalized keratinocytes and reconstructed epidermis.

Calcipotriol is a vitamin D derivative. In vitro data suggest that it induces differentiation and suppresses proliferation of keratinocytes. This is the proposed basis for its effect in psoriasis

The active ingredients in Enstilar Cutaneous Foam are calcipotriol (as monohydrate) and betamethasone (as dipropionate). Enstilar contains a combination of calcipotriol and betamethasone dipropionate. Calcipotriol is a vitamin D analogue. In vitro data suggest that calcipotriol induces differentiation and suppresses proliferation of keratinocytes. This is the proposed basis for its effect in psoriasis. Betamethasone dipropionate is a potent topical corticosteroid with anti-inflammatory, antipruritic, vasoconstrictive and immunosuppressive properties, although it does not cure the underlying condition.

Cream for plaque psoriasis containing calcipotriol 50 mcg/g and betamethasone 0.5 mg/g equivalent.