Aldara

A cutaneous solution containing 5 mg of fluorouracil and 100 mg of salicylic acid per 1g of solution.

Topical cytostatic cream preparation with 5% fluorouracil that exerts a beneficial therapeutic effect on neoplastic and pre-neoplastic skin lesions without damaging normal skin. The pattern of response follows this sequence: erythema, vesiculation, erosion, ulceration, necrosis and epithelialisation. Formerly Efudix.

An ointment for actinic keratosis containing 10mg/g tirbanibulin, applied daily over a 5-day course.

After topical application of Metvix (methyl aminolevulinate), porphyrins accumulate intracellularly in the treated skin lesions. The intracellular porphyrins (including PplX) are photoactive, fluorescing compounds and, on light activation in the presence of oxygen, singlet oxygen is formed, which causes damage to cellular compartments, in particular the mitochondria. Light activation of accumulated porphyrins leads to a photochemical reaction and thereby phototoxicity to the light-exposed target cells

An NSAID gel for actinic keratosis containing 3% diclofenac.

Cream with 3.75% imiquimod, is an immune response modifier that is the lead compound of the imidazoline family.