Diprosalic contains betamethasone dipropionate, a synthetic fluorinated corticosteroid equivalent to 0.05% betamethasone. It also contains 3% salicylic acid. It is active topically, and produces a rapid and sustained response in inflammatory dermatoses that normally respond to topical corticosteroid therapy. It is also effective in less responsive conditions, such as psoriasis of the scalp and chronic plaque psoriasis of the hands and feet, but not in widespread plaque psoriasis. Topical salicylic acid softens keratin, loosens cornified epithelium and desquamates the epidermis allowing more rapid access to the dermis than when applying steroid alone.