Dermatology Handbook

The professional's guide to product selection

Products

Differin

Adapalene is a retinoid-like compound that has been demonstrated to have anti-inflammatory properties

Diflucan

Diflucan contains fluconazole, a triazole antifungal agent. Its primary mode of action is the inhibition of fungal cytochrome P-450-mediated 14 alpha-lanosterol demethylation, an essential step in fungal ergosterol biosynthesis. The accumulation of 14 alpha-methyl sterols correlates with the subsequent loss of ergosterol in the fungal cell membrane and may be responsible for the antifungal activity of fluconazole. Fluconazole has been shown to be more selective for fungal cytochrome P-450 enzymes than for various mammalian cytochrome P-450 enzyme systems

Diprosalic Ointment

Diprosalic contains betamethasone dipropionate, a synthetic fluorinated corticosteroid equivalent to 0.05% betamethasone. It also contains 3% salicylic acid. It is active topically, and produces a rapid and sustained response in inflammatory dermatoses that normally respond to topical corticosteroid therapy. It is also effective in less responsive conditions, such as psoriasis of the scalp and chronic plaque psoriasis of the hands and feet, but not in widespread plaque psoriasis. Topical salicylic acid softens keratin, loosens cornified epithelium and desquamates the epidermis allowing more rapid access to the dermis than when applying steroid alone.

Diprosalic Scalp Application

Diprosalic scalp applications contain the dipropionate ester of betamethasone, equivalent to 0.5% betamethasone, which is a glucocorticoid synthetic fluorinated corticosteroid exhibiting the general properties of corticosteroids, and 2.0% w/w salicylic acid, which has keratolytic properties. The lotion is applied topically to the scalp in the treatment of hyperkeratotic and scaling conditions, where its keratolytic action facilitates penetration of the corticosteroid.

Diprosone

Diprosone contains betamethasone dipropionate, a synthetic fluorinated corticosteroid equivalent to 0.05% betamethasone. It is active topically and produces a rapid and sustained response. Topical corticosteroids such as this are effective in the treatment of a range of dermatoses due to their anti-inflammatory and antipruritic actions.

Doublebase Dayleve Gel

Doublebase Dayleve Gel is a long-lasting highly emollient and protective hydrating base. It may also be used as an adjunct to other topical treatments. The oily ingredients, isopropl myristate and liquid paraffin, encourage rehydration and softening of dry skin by forming an occlusive barrier within the skin surface, thus reducing drying as a result of the evaporation of water diffusing from the underlying layers. Can be used as little as twice a day, morning and night

Doublebase Emollient Bath Additive

Doublebase Emollient Bath Additive contains 65% liquid paraffin, which has moisturising and skin-softening properties, and is specially formulated to disperse in bath water

Doublebase Emollient Shower Gel and Doublebase Emollient Wash Gel

Doublebase Emollient Shower Gel and Doublebase Emollient Wash Gel are designed to deliver emollient ingredients into the stratum corneum when gently applied to areas of dry skin. They are relatively non-greasy, despite their high oil content. The oily ingredients, isopropyl myristate and liquid paraffin, encourage rehydration and softening of dry skin by forming an occlusive barrier within the skin surface, which reduces drying resulting from evaporation of water diffusing from the underlying layers. Both products are suitable for use as a soap substitute owing to the presence of a non-ionic emulsifier (cetomacrogol)

Doublebase Gel

Doublebase Gel is a highly emollient and protective hydrating base. It may also be used as an adjunct to other topical treatments. The oily ingredients, isopropyl myristate and liquid paraffin, encourage rehydration and softening of dry skin by forming an occlusive barrier within the skin surface, thus reducing drying as a result of the evaporation of water diffusing from the underlying layers

Doublebase Once

Doublebase Once is a once daily, highly moisturising and protective emollient gel for the management of dry skin conditions such as eczema, psoriasis and ichthyosis. An advanced gel formulation, specially formulated to provide at least 24 hours’ hydration from one application. An effective, easy to apply alternative to ointments for patient convenience.