Dermatology Handbook

The professional's guide to product selection

Products

Adex Gel

Simple first-line treatment for dry skin prone to inflammation. It is a highly moisturising and protective emollient, which contains an anti-inflammatory medicinal substance, nicotinamide, to help reduce inflammation and redness. Adex Gel does not contain steroids and can be used all over the body for as long as necessary, whether only occasionally, such as during eczema flares

Aklief

Aklief cream contains 50 micrograms (mcg/g) (w/w) trifarotene, which is a chemically stable, terphenyl acid derivative with retinoid-like activity. It is a potent RARγ agonist (retinoid acid receptor γ agonist), characterized by its high specificity to this receptor over RARα & RARβ (50- and 8-fold, respectively, with no Retinoid X Receptor (RXR) activity). In addition, trifarotene modulates retinoid target genes (differentiation and inflammatory processes) in immortalized keratinocytes and reconstructed epidermis.

Aktilite CL128 Lamp

The Aktilite CL128 lamp with light-emitting diodes (LEDs) is intended for use in photodynamic therapy in combination with Metvix (methyl aminolevulinate) cream 160mg/g. The LED array is placed in a rectangular pattern and is coupled to a matching array of lenses that produce a collimated red light beam. The lamp emits a light of high uniformity with a narrow spectrum at approximately 630nm, which can be adjusted by a control panel. The light dose used is 37 J/cm2 and is combined with Metvix cream. The dose is averaged over the treatment area. To be used with professional protective glasses and patient protective goggles

Alacare

After topical application of 5-aminolevulinic acid, protoporphyrin IX (PPIX) accumulates intracellularly in the treated actinic keratosis lesions. The intracellular PPIX is a photoactive, fluorescing compound and, upon light activation in the presence of oxygen, singlet oxygen is formed which causes damage to cellular compartments of the light-exposed target cells, in particular the mitochondria.

Aldara

Aldara

Cream containing 5% imiquimod, an immune response modifier that is effective against viral infections and acts as an anti-tumour agent, principally by induction of alpha interferon and other cytokines.

Alhydran

A specialist after-care treatment for the treatment and hydration of burnt, damaged or vulnerable skin immediately after wound closure. Combines the strength of freshly processed, pure aloe vera gel (Aruba Aloe barbadensis) and high-quality oils and ingredients such as jojoba oil, vitamin E and vitamin C. Helps to prevent scar formation and reduces itching and redness of the skin. Hydrates dry, sensitive and vulnerable skin and improves the flexibility of tight, non-elastic skin affected by burns and scalds. Also available with an integral SPF 30 sun block

Alitretinoin (Toctino)

Contains a retinoid alitretinoin. The pharmacological action of retinoids may be explained by their effects on cell proliferation, cell differentiation, apoptosis, angiogenesis, keratinisation, sebum secretion and immunomodulation. Unlike other retinoids, which are specific agonists of either RAR or RXR receptors, alitretinoin binds to members of both receptor families. The mechanism of action of alitretinoin in chronic hand eczema is unknown. Alitretinoin has demonstrated immunomodulatory and anti-inflammatory effects that are relevant to skin inflammation