Dermatology Handbook

The professional's guide to product selection

Products

Infliximab (Remicade)

Remicade 100mg (infliximab) powder for concentrate for solution for infusion. Infliximab is a chimeric human-murine IgG1 monoclonal antibody produced in murine hybridoma cells by recombinant DNA technology. After reconstitution each ml contains 10mg of infliximab.

Isotretinoin (RoAccutane)

Retinoid. Isotretinoin is a stereoisomer of all-trans retinoic acid (tretinoin). The exact mechanism of action of isotretinoin has not yet been elucidated in detail, but it has been established that the improvement observed in the clinical picture of severe acne is associated with suppression of sebaceous gland activity and a histologically demonstrated reduction in the size of the sebaceous glands. Furthermore, a dermal anti-inflammatory effect of isotretinoin has been established

Ixekizumab (Taltz)

Ixekizumab is an IgG4 monoclonal antibody that binds with high affinity (<3 pM) and specificity to interleukin 17A (both IL-17A and IL-17A/F). Elevated concentrations of IL-17A have been implicated in the pathogenesis of psoriasis by promoting keratinocyte proliferation and activation, as well as in the pathogenesis of psoriatic arthritis by driving inflammation leading to erosive bone damage and pathological new bone formation. Neutralisation of IL-17A by ixekizumab inhibits these actions.

Kamillosan

Kamillosan contains chamomile, which soothes redness, soreness and inflammation associated with a wide range of skin conditions.

Kelo-Cote

Kelo-Cote

Clinically-proven, topical silicone gel for the management and prevention of old and new scars. It is self-drying and forms a bond with the outer layer of skin cells to form a flexible, breathable, waterproof barrier, providing hydration and protection to the scar. This creates an environment which allows the scar to mature through normalised collagen synthesis cycles and improves the physiological and cosmetic appearance of the scar. Kelo-cote is available with additional UV SPF 30 for areas that require additional protection, such as face, neck and hands, and a spray, ideal for joints, flexures, hairy areas or sensitive scars such as those caused from burns.

Klisyri 10mg/g Ointment

An ointment for actinic keratosis containing 10mg/g tirbanibulin, applied daily over a 5-day course.