Dermatology Handbook

The professional's guide to product selection

Products

Duac Once Daily

Duac Once Daily gel has a combination of mild keratolytic and antibacterial properties that act against inflamed lesions of mild to moderate acne vulgaris. Benzoyl peroxide is mildly keratolytic, acting against comedones at all stages of their development. It is an oxidising agent with bactericidal activity against Propionibacterium acnes, the organism implicated in acne vulgaris. It is also sebostatic, counteracting the excessive sebum production associated with acne. Clindamycin is a lincosamide antibiotic with bacteriostatic action against Gram-positive aerobes and a wide range of anaerobic bacteria

Duofilm

Duofilm is a combination of lactic and salicylic acid. Lactic acid affects the keratinisation process, reducing hyperkeratosis, which is characteristic of warts. It is caustic, which leads to the destruction of the keratotic tissue of the wart and causative virus. Salicylic acid is keratolytic, facilitating desquamation by solubilising the intercellular cement in the stratum corneum

Dupilumab (Dupixent)

Dupilumab is a biologic fully human monoclonal antibody against interleukin (IL)-4 receptor alpha that inhibits IL-4/IL-13 signalling, produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.